400 mg film-coated tablets
- Antiviral for systemic use. Direct acting antivirals.
- Sofosbuvir is a pan-genotypic inhibitor of the HCV NS5B RNA-dependent RNA polymerase, which is essential for viral replication. Sofosbuvir is a nucleotide prodrug that undergoes intracellular metabolism to form the pharmacologically active uridine analog triphosphate (GS-461203), which can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator.
- HEPCINAT is indicated in combination with other medicinal products for the treatment of chronic hepatitis C (CHC).