62.5 mg film-coated tablets, 125 mg film-coated tablets
- Antihypertensives for pulmonary arterial hypertension.
- Bosentan is a dual endothelin receptor antagonist (ERA) with an affinity for both endothelin A and B (ETA and ETB) receptors. Bosentan decreases both pulmonary and systemic vascular resistance resulting in increased cardiac output without increasing heart rate.
- BOZENTAN is approved for the treatment of pulmonary arterial hypertension.