Lyophilisate for concentrate for solution for infusion
- Antineoplastic agents. Alkylating agents.
- BENDAMUSTINE hydrochloride is an alkylating antitumor agent with a unique activity. The antineoplastic and cytocidal effect of bendamustine hydrochloride is based essentially on a cross-linking of DNA single and double strands by alkylation. As a result, DNA matrix functions and DNA synthesis and repair are impaired.
- BENDAMUSTINE is approved for three indications: chronic lymphocytic leukaemia (CLL), advanced indolent non-Hodgkin´s lymphomas (NHL) in rituximab-refractory patients and advanced multiple myeloma (MM).
- BENDAMUSTINE is including in the World Health Organization’s List of Essential Medicines