Film-coated tablet 2,5 mg

  • Antithrombotic agents, direct factor Xa inhibitors.
  • Apixaban is a potent, oral, reversible, direct and highly selective active site inhibitor of factor Xa. It inhibits free and clot-bound factor Xa, and prothrombinase activity. As a result, apixaban prevents thrombin generation and thrombus development.
  • APIXA is approved in adults for three indications: prevention of venous thromboembolic events (VTE) in patients who have undergone elective hip or knee replacement surgery, prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and prevention of recurrent DVT and PE.