Lyophilised powder for solution for injection
- Antineoplastic agents. Other antineoplastic agents.
- Proteasome inhibitor. Reversibly and selectively inhibits the activity of 26S proteasome, a large protein complex that degrades ubiquitinated proteins. The ubiquitin-proteasome pathway plays an essential role in regulating the turnover of specific proteins, thereby maintaining homeostasis within cells. Inhibition of the 26S proteasome prevents this targeted proteolysis and affects multiple signaling cascades within the cell, ultimately resulting in cancer cell death.
- It is used to treat multiple myeloma and mantle cell lymphoma.